Professeur Frank Hertel

Professeur Frank Hertel

  • 10/05/1967 Born in Kusel / Pfalz / Germany
  • 1973 - 1977 Primary School Selberg in Rothselberg
  • 1977 - 1979 Realschule in Kusel
  • 1979 - 1986 College (Gymnasium) in Kusel
  • 1986 Abitur in Kusel


School / University Studies

  • 1986 - 1988 Studies on Eelectrical Engineering, University Kaiserslautern              
  • 1988 - 1993 Studies in Human Medicine, University Mainz                               

Practical Year:

  • Université Louis Pasteur Strasbourg / Neurologie (Prof. M. Collard)
  • Neurosurgery University Homburg / Saar (Prof. W.I. Steudel)
  • Internal Medicine, Traumatology, University Homburg / Saar

3rd Staatsexamen in Homburg 1994



Die Expression von E - Cadherin in Tumoren des menschlichen Nervensystems - eine immunhistologische und immunelektronenmikroskopische Untersuchung.

Neuropathology / Neurosurgery, University Mainz (Prof. H.H. Goebel, Prof. A. Perneczky)

Magna cum laude



  • German
  • English, French, Luxemburgish


Neurosurgical Training / Career

  • 1994 - 1995 Neuropathology, University Mainz (Prof. H.H. Goebel)
  • 1995 - 1996 Neurosurgery, University Mainz (Prof. A. Perneczky)   
  • 1996 - 2000 Neurosurgery, Brüderkrankenhaus Trier (Prof. K. Faulhauer)
  • 2000 - 2007 Neurosurgery, Brüderkrankenhaus Trier (Prof. M. Bettag)
  • Since 2001 Specialized in Neurosurgery
  • 2001 - 2003 Chief Resident (Funktionsoberarzt) 
  • 2003 - 2007 Senior Physician (Oberarzt) 
  • 2007 - 2008 Head of Neurosurgical Department, SHG Hospital, Idar-Oberstein,  Germany
  • Since 2008 Head of Neurosurgical National Department of Luxemburg, Centre Hospitalier de Luxembourg
  • Since 2008 (additionally) Cooperative Functional Neurosurgeon, Neurosurgery, Idar-Oberstein


Additional  Studies and Activities

  • Since 2009 Vicepresident of the German Neuromodulation Society (DGNM, German section of the INS)
  • 2006 Cofounder of interdisciplinary center of excellence neurotechnology (IKNTEC)
  • Management of Health Care Institutions – Distance Study: University Kaiserslautern (Grade 1)
  • Certificate as : Pruefarzt fuer Klinische Studien (research coordinator for clinical trials), University Duesseldorf, 2005
  • Various national and international research projects on functional and oncological neurosurgery, especially at: Brain – computer interface, Neurostimulation Techniques and Nanoparticles
  • Constitution of study group for brain tumours  (cooperation with Euromedizinalkolleg für med. Dokumentare, database of approximately 1000 neurooncological patients)
  • Participation at NOA III survey (glioma therapy)
  • Participation at survey of EORTC for the evaluation of a quality of life measuring instrument for neurooncological patients
  • Participation at nationwide survery for the treatment of primary CNS lymphoma (series of 30 tumours in Trier)
  • Founding and accompanying of a patient’s group for neuroncological patients (1998-2008) in Trier
  • Ongoing prospective study: ADAPT, Prospective tissue and data collection of brain tumor patients ( Cooperation: Dep Neurosurgery CHL, NorluxLab, CRP, Luxemburg)
  • Ongoing prospective multicenter study: Evaluation of epidural pulsed high frequency stimulation for chronic pain (Dep Neurosurgery CHL, Neurosurgery Bonn, Orthopedic Surgery Schwerte, OMT Minden, Germany, CRP Luxemburg)
  • Retrospective study on epidural high frequency pulsed spinal stimulation for chronic pain (Dep Neurosurgery CHL, OMT Minden, CRP Luxemburg)
  • Participation in a European multicenter RELIEF trial: Prospective trial on stimulation of the suboccipital nervs for chronic therapy resistant migraine



Vice President German Neuromodulation Society since 2009

Member of the executive committee of the Neurological Society of Luxemburg since 2008

  • German Neurosurgery Society (Deutsche Gesellschaft für Neurochirurgie)
  • German Neuropathology and Neuroanatomy Society (Deutsche Gesellschaft für Neuropathologie und Neuroanatomie)
  • European Neurosurgery Society
  • Movement Disorders Society
  • German Cancer Society, Neurooncological Working Group (Deutsche Krebsgesellschaft)
  • German Society fort he Study of Pain (Deutsche Gesellschaft zum Studium des Schmerzes)
  • Deutsche Wirbelsaeulengesellschaft (German Spine Surgery Society)
  • Eurospine (European Spine Society)
  • AG Tiefe Hirnstimulation (Working Group on Deep Brain Stimulation)
  • German Neuromodulation Society (DGNM)
  • Neurological Society Luxemburg (SLN)


Research Projects 

  • Cooperation with Institute for Innovative Informatics Applications at Trier University of Applied Sciences (signal and image processing for functional neurosurgeries, robotics, neural networks, group of 1 professor, 2 research assistants and various students)
  • Cooperation with Institute for Neurosurgical Pathophysiology at University of Mainz (Prof. Kempski) and Saarland University (Biochemistry for innovative treatment strategies of malign gliomas, 1 doctorand, 1 veterinarian and 1 neuropathologist)
  • Neuropsychological survery (for the hemisphere-dependent analysis of cognitive performance pre- and post-stimulation oft he subthalamic nucleus, 1 neuropsychologist and 1 student)  
  • Retrospective investigation of subgroup analysis of brain tumour patients (1 study nurse and 1 intern)
  • Close cooperation with Neurpathology at Histology Centre Trier (Prof. Feiden)


Selected Publications

Timmermann L, Schüpbach M, Hertel F, Wolf E, Eleopra R, Franzini A, Servello D, Skogseid IM, Rumia J, Aliaga AS, Barbe MT, Pauls KA, Lin JP, Moro E, Lloyd A, Maarouf M. A New Rechargeable Device for Deep Brain Stimulation: A Prospective Patient Satisfaction Survey. Eur Neurol. 2013 Jan 10, 69(4), 193-199


Golebiewska A., Bougnaud S., Stieber D., Brons N., Vallar L., Hertel F., Klink B., Schroeck E., Bjerkvig R., Niclou S.: Side population in human glioblastoma is non-tumorigenic and charcatrizes brain endothelial cells.

Accepted for Brain, 2013


Lueken U, Schwarz M, Hertel F, Schweiger E, Wittling W. Impaired performance on the Wisconsin Card Sorting Test under left- when compared to right-sided deep brain stimulation of the subthalamic nucleus in patients with Parkinson's disease. J Neurol. 2008 Dec, 255(12), 1940-8


Bernard F, Gemmar P, Husch A, Hertel F. Improvements on the Feasibility of Active Shape Model-based Subthalamic Nucleus Segmentation. Biomed Tech (Berl). 2012 Aug 24. doi:pii: /j/bmte.2012.57.issue-s1-B/bmt-2012-4333/bmt-2012-4333.xml. 10.1515/bmt-2012-4333. [Epub ahead of print] PubMed PMID: 22944839


F. Hertel, M. Zürcher, C. Decker, P. Gemmar, B. Noll, M. Bettag: Implantation of electrodes for deep brain stimulation of the subthalamic nucleus in advanced Parkinsons's Disease with the aid of intraoperative microrecording under general anathesia, Neurosurgery, 2006  


Hertel F, Walter C, Bettag M, Mörsdorf M. Perfusion-weighted magnetic resonance imaging in patients with vasospasm: a useful new tool in the management of patients with subarachnoid hemorrhage.  Neurosurgery. 2005, 56(1), 28-35c


Hertel F, Walter C, Bettag M, Mörsdorf M. Perfusion-weighted magnetic resonance imaging in patients with vasospasm: a useful new tool in the management of patients with subarachnoid hemorrhage.  Neurosurgery. 2005, 56(1), 28-35


Hana A, Husch A, Hana A, Boecher-Schwarz H, Hertel F. DTI of the visual pathway in cerebral lesions. Bull Soc Sci Med Grand Duche Luxemb. 2012;(2):15-24. PubMed PMID: 23362563.


Book Contributions 

Stereotaktische Behandlung von Tremorerkrankungen in: Vaskulaere Neurochirurgie, Funktionelle Neurochirurgie, Thieme Verlag 2011, A. Raabe, V. Rode (Edts.)

Onkologie: Interdisziplinäre Empfehlungen zur Therapie. Zuckschwerdt Verlag (regular revisions of chapters on Glioma and CNS-Lymphoma)

Integrative Onkologie. Elsevier-Verlag, Urban und Schwarzenberg, Freiburg (coauthor and author of various chapters on neurooncology)

Computergestützte Hirnchirurgie in: Medizin des 21. Jahrhunderts, 2001, Springer Verlag, Heidelberg (coauthor)

20378 Frank Hertel
CHL - CHL Centre


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